|
rs1144507
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested the hypothesis that a common variant in ZNF202, A154V, predicts risk of ischemic heart disease (IHD), myocardial infarction (MI), and ischemic cerebrovascular disease (ICVD).
|
16289551 |
2006 |
|
rs6993770
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on 9 SNPs independently predicting VEGF (rs1740073 [<i>C6orf223</i>], rs2375981 [<i>KCNV2</i>], rs2639990 [<i>ZADH2</i>], rs4782371 [<i>ZFPM1</i>], rs6921438 [<i>LOC100132354</i>], rs7043199 [<i>VLDLR-AS1</i>], rs10761741 [<i>JMJD1C</i>], rs6993770 [<i>ZFPM2</i>], and rs114694170 [<i>MEF2C</i>]), VEGF was unrelated to IHD (odds ratio 0.99 per log-transformed pg/mL, 95%CI 0.96-1.02) using inverse variance weighting.
|
28765276 |
2017 |
|
rs4782371
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on 9 SNPs independently predicting VEGF (rs1740073 [<i>C6orf223</i>], rs2375981 [<i>KCNV2</i>], rs2639990 [<i>ZADH2</i>], rs4782371 [<i>ZFPM1</i>], rs6921438 [<i>LOC100132354</i>], rs7043199 [<i>VLDLR-AS1</i>], rs10761741 [<i>JMJD1C</i>], rs6993770 [<i>ZFPM2</i>], and rs114694170 [<i>MEF2C</i>]), VEGF was unrelated to IHD (odds ratio 0.99 per log-transformed pg/mL, 95%CI 0.96-1.02) using inverse variance weighting.
|
28765276 |
2017 |
|
rs2639990
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on 9 SNPs independently predicting VEGF (rs1740073 [<i>C6orf223</i>], rs2375981 [<i>KCNV2</i>], rs2639990 [<i>ZADH2</i>], rs4782371 [<i>ZFPM1</i>], rs6921438 [<i>LOC100132354</i>], rs7043199 [<i>VLDLR-AS1</i>], rs10761741 [<i>JMJD1C</i>], rs6993770 [<i>ZFPM2</i>], and rs114694170 [<i>MEF2C</i>]), VEGF was unrelated to IHD (odds ratio 0.99 per log-transformed pg/mL, 95%CI 0.96-1.02) using inverse variance weighting.
|
28765276 |
2017 |
|
rs7043199
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on 9 SNPs independently predicting VEGF (rs1740073 [<i>C6orf223</i>], rs2375981 [<i>KCNV2</i>], rs2639990 [<i>ZADH2</i>], rs4782371 [<i>ZFPM1</i>], rs6921438 [<i>LOC100132354</i>], rs7043199 [<i>VLDLR-AS1</i>], rs10761741 [<i>JMJD1C</i>], rs6993770 [<i>ZFPM2</i>], and rs114694170 [<i>MEF2C</i>]), VEGF was unrelated to IHD (odds ratio 0.99 per log-transformed pg/mL, 95%CI 0.96-1.02) using inverse variance weighting.
|
28765276 |
2017 |
|
rs2010963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, VEGF rs699947 and rs2010963 polymorphisms may serve as genetic biomarkers of poor collateral circulation after myocardial ischemia.
|
30317903 |
2018 |
|
rs699947
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, VEGF rs699947 and rs2010963 polymorphisms may serve as genetic biomarkers of poor collateral circulation after myocardial ischemia.
|
30317903 |
2018 |
|
rs6742078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
UGT1A1 rs6742078 TT versus GG genotype was associated with 95% increased bilirubin levels (P < 0.001); TT versus GG genotype was associated with odds ratios (ORs) of 1.03 (95% CI, 0.96-1.11; P = 0.73) for IHD and 1.01 (95% CI, 0.92-1.12; P = 0.68) for MI.
|
22805420 |
2013 |
|
rs2295490
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In 100 additional type 2 diabetic patients who suffered from myocardial ischemia, age at myocardial ischemia was progressively and significantly (P = 0.03) reduced from Q84Q to Q84R to R84R individuals.
|
16123373 |
2005 |
|
rs745738344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The emerging data are quite conflicting and do not provide definitive evidence for a role of these gene variants in the pathogenesis of IHD; a possible exception is the G252A and polymorphism in the TNF-beta gene (also known as lymphotoxin-alpha) which, in a comprehensive genome-scan linkage analysis of unrelated Japanese, but not in a smaller German population, was linked to myocardial infarction.
|
15760675 |
2005 |
|
rs4986791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In order to clarify the potential impact of TLR4 polymorphisms on the predisposition for DM2 as well as on diabetes-related IHD vulnerability, the distribution of the mutant TLR4 Asp299Gly and Thr399Ile alleles in 286 DM2 patients and 413 non-DM2 controls with or without IHD, was examined.
|
21628510 |
2011 |
|
rs1042579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Several published studies have shown that the Ala455Val thrombomodulin polymorphism is associated with ischemic heart disease, but none has examined the association with stroke.
|
15574195 |
2004 |
|
rs147377392
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Several published studies have shown that the Ala455Val thrombomodulin polymorphism is associated with ischemic heart disease, but none has examined the association with stroke.
|
15574195 |
2004 |
|
rs1800470
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Leu(10)-->Pro (codon 10) polymorphism in the TGF-beta1 gene is associated with end-stage heart failure caused by dilated CMP and not with IHD.
|
11557193 |
2001 |
|
rs7903146
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pilot cohort study on the potential role of TCF7L2 rs7903146 on ischemic heart disease among non-diabetic kidney transplant recipients.
|
28299838 |
2017 |
|
rs4717806
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among genetic polymorphisms, rs4717806(A) and r</span>s2293489(T), as well as the rs4717806 - rs2293489 (A-T) haplotype were associated with higher risk for IHD (Pc = .02; Pc = .02; P = .04, respectively).
|
31192914 |
2019 |
|
rs1022113606
|
|
|
0.040 |
GeneticVariation |
BEFREE |
An R213G single nucleotide polymorphism (SNP) has been shown to alter levels of EC-SOD and patient outcomes in chronic obstructive pulmonary disease (COPD) and ischemic heart disease.
|
18948423 |
2009 |
|
rs1022113606
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Substitution of arginine by glycine at amino acid 213 (R213G) of its HBD was first identified in patients with heart failure, followed by many studies that focused on the role of this variant (SOD3(R213G)) in ischemic heart disease and cardiovascular disease.
|
25927599 |
2015 |
|
rs1022113606
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Previously, R213G heterozygosity has been associated with a decreased risk of chronic obstructive pulmonary disease (COPD) and an increased risk of ischemic heart disease (IHD).
|
26901385 |
2016 |
|
rs1022113606
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Among those who died, the incidence of ischemic heart disease and cerebrovascular disease in cases with R213G was significantly higher than in cases without R213G.
|
10720891 |
2000 |
|
rs1799895
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Substitution of arginine by glycine at amino acid 213 (R213G) of its HBD was first identified in patients with heart failure, followed by many studies that focused on the role of this variant (SOD3(R213G)) in ischemic heart disease and cardiovascular disease.
|
25927599 |
2015 |
|
rs1799895
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Among those who died, the incidence of ischemic heart disease and cerebrovascular disease in cases with R213G was significantly higher than in cases without R213G.
|
10720891 |
2000 |
|
rs1799895
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Previously, R213G heterozygosity has been associated with a decreased risk of chronic obstructive pulmonary disease (COPD) and an increased risk of ischemic heart disease (IHD).
|
26901385 |
2016 |
|
rs1799895
|
|
|
0.040 |
GeneticVariation |
BEFREE |
An R213G single nucleotide polymorphism (SNP) has been shown to alter levels of EC-SOD and patient outcomes in chronic obstructive pulmonary disease (COPD) and ischemic heart disease.
|
18948423 |
2009 |
|
rs363050
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed if genetic variants of the SNARE genes are associated with IHD.SNAP25 rs363050, Stx-1A rs4717806, rs2293489, and VAMP2 26bp ins/del genetic polymorphisms were analyzed in a cohort of 100 participants who underwent heart surgery; 56 of them were affected by IHD, while 44 were not.
|
31192914 |
2019 |